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Surgical adjunctive use of Cryopreserved Umbilical Amnion in the Successful Management of Post-Traumatic, Complex Wounds

We report the technique of applying cryopreserved umbilical amnion to successfully manage post-traumatic, complex wounds with exposed bone, muscle, or tendon

Limb salvage with adjunctive umbilical cord
post-traumatic, complex wounds with exposed bone, muscle, or tendon
active infection without antibiotics
Applied in-office or OR
preop IV antibiotics general anesthesia
wound VAC
+: biological anti-inflammatory and anti-scarring properties -: need to ensure the graft stays on wound until dissolved
infection, bleeding, loss of motion
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Stewart C. Human Umbilical Cord & Amniotic Membrane Reduces Pain, Augments Healing of Acute Trauma Wounds. https://www.hmpgloballearningnetwork.com/site/twc/articles/human-umbilical-cord-amniotic-membrane-reduces-pain-augments-healing-acute-trauma-wounds Singer AJ, Hollander JE, Quinn JV. Evaluation and management of traumatic lacerations. N Engl J Med. 1997;337:1142–8 Raas C, Attal R, Kaiser P, Popovscaia M, Zegg M. Treatment and outcome with traumatic lesions of the olecranon and prepatellar bursa: a literature review apropos a retrospective analysis including 552 cases. Arch Orthop Trauma Surg. 2017 Jun;137(6):823-827. doi: 10.1007/s00402-017-2690-2. Epub 2017 Apr 26. PMID: 28447166. Müllner T, Mrkonjic L, Kwasny O, Vécsei V. The use of negative pressure to promote the healing of tissue defects: a clinical trial using the vacuum sealing technique. Br J Plast Surg. 1997 Apr;50(3):194-9. doi: 10.1016/s0007-1226(97)91369-2. PMID: 9176007. Redett RJ, Robertson BC, Chang B, Girotto J, Vaughan T. Limb salvage of lower-extremity wounds using free gracilis muscle reconstruction. Plast Reconstr Surg. 2000 Dec;106(7):1507-13. doi: 10.1097/00006534-200012000-00010. PMID: 11129178.

Review Surgical adjunctive use of Cryopreserved Umbilical Amnion in the Successful Management of Post-Traumatic, Complex Wounds.

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